Patrick Ryan may refer to:

• Patrick Ryan (American author) (born 1965), American novelist and editor
• Patrick Ryan (English author) (1916–1989), English author
• Patrick Ryan (hammer thrower) (1881–1964), U.S. Olympic athlete and New York City police officer
• Patrick Ryan (Irish politician) (1898–1944), Irish Sinn Féin politician from Tipperary
• Patrick Ryan (Irish priest) (born 1930), Irish Catholic priest and alleged IRA supplier
• Patrick Ryan (wheelchair rugby) (born 1981), Australian Paralympic wheelchair rugby union player
• Patrick Ryan, president of Loyola Jesuit College, 1999–2005
• Patrick Ryan, voice actor of Nightmare in Soulcalibur III
• Patrick D. Ryan (1920–2004), mayor of Galway from 1962 to 1963
• Patrick G. Ryan (1838–1906), leather manufacturer and political figure in New Brunswick
• Patrick J. D. Ryan, member of the States of Jersey
• Patrick J. Ryan (chaplain) (1902–1975), Chief of Chaplains of the U.S. Army
• Patrick J. Ryan (New York judge) (1861–1940), American lawyer, politician, and judge from New York
• Patrick John Ryan (1831–1911), Irish-American bishop
• Patrick Joseph Ryan (1904–1969), Australian anti-communist priest
• Patrick Kevin "Pat" Ryan (born 1982), American politician
• Patrick W. Ryan (died 1993), Irish politician
• Paddy Ryan (1851–1900), Irish-American boxer
• Pat Ryan (executive) (Patrick G. Ryan), founder and retired executive chairman of Aon Corporation
• Patrick Finbar Ryan, Archbishop of Port of Spain